Boro cut for the drop after loss to Watford
MIDDLESBROUGH are 3-1 to be relegated from the Premier League after a bitterly disappointing 1-0 home defeat to Watford.
Jose Holebas's stunning second-half strike proved to be the difference at the Riverside, leaving Boro down in 17th spot.
Boro boss Aitor Karanka is 7-1 with Paddy Power to be the next Premier League manager to leave his current position with Sunderland's David Moyes the odds-on favourite at 5-6.
It was a first clean sheet of the season for Watford and the Hornets have drifted out to 11-1 for relegation.
Southampton were comfortable 3-1 winners over Burnley at St Mary's. Charlie Austin scored twice and Nathan Redmond was also on target for Saints.
Huddersfield were unable to move back to the top of the Sky Bet Championship after they lost 1-0 at home to Sheffield Wednesday.
Fernando Forestieri's second-half penalty saw Wednesday move up to seventh.