Tottenham bring City's winning run to an end
Manchester City's 15-match Premier League winning run ended when the champions drew 2-2 with Totenham at the Etihad.
The Citizens had an injury-time goal from Gabriel Jesus ruled out by VAR, to reward punters who backed the draw at 9-2.
Tottenham had twice come from behind with goals from Erik Lamela and Lucas Moura after Raheem Sterling and Sergio Aguero struck for City.
Liverpool showed no ill-effects from their Istanbul Super Cup trip as they claimed a 2-1 win at Southampton, their 11th consecutive Premier League victory.
Sadio Mane set the Reds on their way and those who backed Jurgen Klopp's team at 1-2 to win at St Mary's breathed more easily when Robeto Firmino added a second.
Former Liverpool forward Danny Ings pulled a goal back for the Saints, who have lost their opening two matches.
Liverpool beat Norwich in the first game of the season and the newly-promoted Canaries had striker Teemu Pukki to thank for a 3-1 win over Newcastle at Carrow Road.
The Finnish centre forward scored a hat-trick and, having scored at Anfield last week, he is 40-1 with Betfair and Paddy Power to be crowned the Premier League's top goalscorer this season.
Norwich are 8-13 with Betfair and Paddy Power to extend their top-flight stay into next term while Steve Bruce's Magpies are 17-10 to be playing in the Sky Bet Championship next August, having also lost their first game at home to Arsenal.
The Gunners claimed a 2-1 victory over Burnley at the Emirates - Alexandre Lacazette and Pierre-Emerick Aubameyang were on target - while Everton won 1-0 at home to Watford.
Bournemouth ensured Aston Villa started their return to the Premier League with two defeats as they won 2-1 at Villa Park, while Brighton and West Ham shared the spoils in a 1-1 draw at the Amex Stadium.