City 2-9 for title after Watford win
Manchester City's seventh straight Premier League victory moved them five points clear at the summit and the champions are only 2-9 to retain the title following the 2-1 win over Watford.
Leroy Sane and Riyad Mahrez were on target at Vicarage Road and preparations now turn to Saturday's crunch clash away to Chelsea.
Such is the dominance of Pep Guardiola's side that bookmakers rate them odds-on at a best-priced 10-11 with Coral to succeed at Stamford Bridge even though star striker Sergio Aguero remains doubtful for the trip having missed the wins over Bournemouth and Watford.
Second-placed Liverpool have the chance to narrow the deficit back to two points at Burnley on Wednesday.
Cardiff are 4-7 to be relegated following a 3-1 defeat at West Ham.
Joe Ralls's first-half penalty miss proved decisive for the Bluebirds, who went in level at the break before Lucas Perez scored twice and Michael Antonio added a third for the hosts.
West Ham lost Marko Arnautovic to injury ahead of Saturday's London derby at home to Crystal Palace which will be a key game for the Eagles after they were thumped 3-1 at arch-rivals Brighton.
Brighton, who had Shane Duffy red carded on 28 minutes, still found themselves 3-0 up at the break thanks to goals from Glenn Murray, Leon Balogun and Florin Andone.
Palace are 9-1 to be relegated and Huddersfield are 4-7 as they went down 2-1 at Bournemouth.
Cherries hitman Callum Wilson notched his eighth Premier League goal of the campaign, moving him two behind leading marksman Pierre-Emerick Aubameyang, and is 40-1 to win the Golden Boot.