Huddersfield relegated from the Premier League
Huddersfield have been relegated from the Premier League with six games remaining after sliding to a 2-0 defeat at Crystal Palace.
Victories for Southampton, who won 1-0 at Brighton, and Burnley, 2-0 victors at home to Wolves, meant a return to the Sky Bet Championship after a two-year absence for the Terriers and a payout for punters who took ante-post relegation quotes of 5-4 from BoyleSports and Sky Bet.
Fulham are almost certain to join them in the second tier after goals from Wes Morgan and Sergio Aguero condemned them to a 2-0 defeat at home to Manchester City.
The Cottagers failed to win a corner or muster a shot on target and they will be officially relegated on Tuesday if they lose to Watford at Vicarage Road.
City's victory lifted them one point above Liverpool. The Reds may finish the weekend at the top of the table but they have been eased to 9-4 in the title betting while City were cut to 4-11.
Aguero's goal, his 19th of the season, opened up a two-goal gap over his rivals in the race for the golden boot.
The Argentinian is 11-8 to top the scoring charts although he was withdrawn in the 57th minute with what appeared to be a muscle injury. City boss Pep Guardiola said he hopes the issue is not too serious and it will be assessed by the club on Sunday.
Southampton took a big stride towards safety thanks to Pierre Hojbjerg's decisive 53rd-minute goal at Brighton.
The Saints are five points above the drop zone and have drifted to 50-1 to finish in the bottom three.
Another team with a five-point buffer are Burnley after Connor Coady's own goal and a Dwight McNeill strike delivered victory over Wolves.
Burnley have eased to 11-2 for a bottom-three finish while third-bottom Cardiff, who take on Chelsea on Sunday, are 1-5 to go down.
Manchester United replaced Arsenal in fourth place after Marcus Rashford and Anthony Martial netted in a 2-1 success over Watford at Old Trafford. The Red Devils are 11-10 to seal a top four finish.
Leicester climbed from tenth to eighth thanks to a 2-0 victory at home to Bournemouth.
Goals from Wes Morgan and Jamie Vardy sealed a fourth win in five for the Foxes, who are level on points with Wolves in the battle for seventh.