Champions Manchester City hammer West Ham
After Liverpool's 4-1 victory over Norwich on Friday, Premier League champions Manchester City went one better, winning 5-0 at West Ham with Raheem Sterling scoring a hat-trick.
The 5-0 scoreline had been a 22-1 chance before kick-off but the 1-4 Citizens swept aside their hosts at the London Stadium with Gabriel Jesus and Sergio Aguero also on target.
Pep Guardiola's side are 1-2 to complete a hat-trick of top-flight titles – Liverpool are 3-1 – while Sterling's Golden Boot odds have been slashed from 14-1 to 6-1.
Tottenham were given a scare by promoted Aston Villa but Tanguy Ndombele's debut goal and a Harry Kane brace gave them a 3-1 home win.
Villa, 10-1 pre-match, took an early lead through John McGinn and traded at 11-10 in-play as Spurs hit 4-1 before scoring three times in the last 20 minutes.
Saturday's 3pm kick-offs featured a couple of handsome 3-0 wins for Burnley, at home to Southampton, and Brighton, away to Watford.
The Seagulls, just 15-8 for relegation at the start of the season, were 7-2 outsiders at Vicarage Road in Graham Potter's first game in charge.
Debutant striker Neal Maupay, a £20 million signing from Brentford, capped a dream day for Potter by scoring the third goal for a Brighton side who found the net only 16 times in 19 away matches under Chris Hughton last season.
Sheffield United picked up a point in their first game back in the Premier League as Billy Sharp's late goal earned the Blades a 1-1 draw at Bournemouth. Chris Wilder's men are 10-11 with Betfair and Paddy Power to stay up.
Crystal Palace versus Everton finished goalless at Selhurst Park. No goalscorer had been 15-2 before the game kicked off.
Sky Bet Championship favourites Leeds were held to a 1-1 draw by Nottingham Forest at Elland Road but Fulham, second favourites for the title, beat Blackburn 2-0.
A major gamble on Coventry went astray in League One as a Bolton side featuring seven teenagers held out for a 0-0 draw.
With five senior players reportedly refusing to turn out for the troubled Trotters, Phil Parkinson had to name a hugely inexperienced side and the Sky Blues were backed from 8-15 on Friday to 1-5 by the time the game kicked off.
Bolton drifted from 5-1 to 18-1 as news of their depleted team spread but the youngsters held out for a point. They are 1-4 to be relegated, however.