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Napoli vs. Real Madrid

Napoli saw over 2.5 land in five of their six group matches last campaign and they're already one from one this season following their 2-1 win away at Braga. Madrid also saw over 2.5 land in four of their six group matches last season and in four of their six Champions League ties away from home.

Lens vs. Arsenal

Arsenal are yet to concede a goal away from home this season and they should have too much attacking talent for a Lens side that have already lost to PSG and Monaco this season. Arsenal have won 11 of their last 17 European away games.

Plymouth vs. Millwall

Plymouth can take advantage of a tough journey for Millwall to the south coast, it's about a four hour drive for The Lions. Plymouth have won three out of four at home, which includes a win over seventh placed Norwich. Millwall have one win away from home this season against Boro and they suffered 10 defeats away from home last season.

Stoke vs. Southampton

Southampton's defensive issues are well documented. They've seen over 2.5 goals land in 89% of matches this year and 100% in away games. Stoke have seen four or more goals in their last three matches.

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