Current Holders: New England
| | HOME | | AWAY | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P | W | D | L | F | A | W | D | L | F | A | GD | Pts | ||
| 1 | Philadelphia U | 32 | 11 | 5 | 0 | 45 | 9 | 7 | 5 | 4 | 23 | 13 | +46 | 64 |
| 2 | Montreal Imp | 32 | 8 | 3 | 5 | 29 | 21 | 10 | 2 | 4 | 30 | 28 | +10 | 59 |
| 3 | NY Red Bulls | 32 | 5 | 5 | 6 | 24 | 22 | 9 | 3 | 4 | 23 | 17 | +8 | 50 |
| 4 | New York City | 32 | 9 | 4 | 3 | 35 | 18 | 5 | 3 | 8 | 18 | 21 | +14 | 49 |
| 5 | Cincinnati | 31 | 6 | 6 | 4 | 35 | 24 | 5 | 6 | 4 | 21 | 26 | +6 | 45 |
| 6 | Orlando City | 31 | 8 | 0 | 8 | 24 | 27 | 5 | 6 | 4 | 16 | 19 | -6 | 45 |
| 7 | Columbus Crew | 31 | 6 | 6 | 4 | 20 | 14 | 3 | 9 | 3 | 21 | 22 | +5 | 42 |
| 8 | Inter Miami CF | 31 | 9 | 3 | 3 | 29 | 24 | 3 | 3 | 10 | 12 | 28 | -11 | 42 |
| 9 | Atlanta U | 32 | 8 | 5 | 3 | 30 | 22 | 2 | 5 | 9 | 16 | 28 | -4 | 40 |
| 10 | New England | 32 | 6 | 6 | 4 | 20 | 15 | 3 | 5 | 8 | 24 | 33 | -4 | 38 |
| 11 | Charlotte FC | 31 | 9 | 0 | 6 | 22 | 14 | 3 | 2 | 11 | 16 | 34 | -10 | 38 |
| 12 | Chicago | 32 | 6 | 4 | 6 | 17 | 16 | 3 | 4 | 9 | 18 | 29 | -10 | 35 |
| 13 | Toronto FC | 32 | 7 | 3 | 6 | 30 | 28 | 2 | 4 | 10 | 19 | 33 | -12 | 34 |
| 14 | DC United | 32 | 4 | 4 | 8 | 20 | 29 | 3 | 2 | 11 | 14 | 36 | -31 | 27 |
| 15 | Los Angeles FC | 32 | 13 | 2 | 1 | 39 | 14 | 7 | 2 | 7 | 25 | 22 | +28 | 64 |
| 16 | Austin FC | 32 | 8 | 5 | 3 | 41 | 22 | 8 | 2 | 6 | 23 | 24 | +18 | 55 |
| 17 | Dallas | 32 | 9 | 4 | 3 | 26 | 14 | 4 | 7 | 5 | 20 | 21 | +11 | 50 |
| 18 | Nashville MLS | 32 | 6 | 6 | 4 | 29 | 19 | 6 | 5 | 5 | 21 | 20 | +11 | 47 |
| 19 | LA Galaxy | 32 | 8 | 3 | 5 | 34 | 24 | 5 | 4 | 7 | 20 | 25 | +5 | 46 |
| 20 | Portland Timb. | 32 | 8 | 6 | 2 | 27 | 17 | 3 | 7 | 6 | 24 | 31 | +3 | 46 |
| 21 | Minnesota U | 32 | 7 | 5 | 4 | 25 | 20 | 6 | 1 | 9 | 21 | 29 | -3 | 45 |
| 22 | Real Salt Lake | 32 | 8 | 5 | 3 | 24 | 14 | 3 | 5 | 8 | 15 | 29 | -4 | 43 |
| 23 | Vancouver W | 32 | 9 | 3 | 4 | 23 | 20 | 2 | 4 | 10 | 15 | 35 | -17 | 40 |
| 24 | Seattle | 31 | 9 | 1 | 5 | 26 | 16 | 3 | 2 | 11 | 18 | 26 | +2 | 39 |
| 25 | Colorado | 32 | 9 | 5 | 2 | 28 | 15 | 1 | 4 | 11 | 16 | 41 | -12 | 39 |
| 26 | Kansas City | 32 | 8 | 2 | 6 | 24 | 17 | 2 | 5 | 9 | 16 | 35 | -12 | 37 |
| 27 | Houston | 32 | 6 | 5 | 5 | 23 | 19 | 3 | 1 | 12 | 17 | 33 | -12 | 33 |
| 28 | San Jose | 32 | 6 | 6 | 4 | 29 | 27 | 1 | 4 | 11 | 19 | 40 | -19 | 31 |
