Current Holders: Philadelphia U
| | HOME | | AWAY | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P | W | D | L | F | A | W | D | L | F | A | GD | Pts | ||
| 1 | New England | 17 | 6 | 0 | 1 | 14 | 8 | 5 | 3 | 2 | 19 | 13 | +12 | 36 |
| 2 | Orlando City | 16 | 5 | 2 | 1 | 16 | 6 | 3 | 2 | 3 | 10 | 15 | +5 | 28 |
| 3 | Nashville MLS | 16 | 6 | 5 | 0 | 22 | 10 | 0 | 4 | 1 | 3 | 5 | +10 | 27 |
| 4 | New York City | 15 | 6 | 1 | 2 | 22 | 8 | 2 | 1 | 3 | 8 | 8 | +14 | 26 |
| 5 | Philadelphia U | 17 | 4 | 2 | 2 | 10 | 7 | 2 | 5 | 2 | 11 | 10 | +4 | 25 |
| 6 | Columbus Crew | 16 | 4 | 3 | 0 | 11 | 5 | 2 | 3 | 4 | 6 | 11 | +1 | 24 |
| 7 | Montreal Imp | 16 | 4 | 2 | 1 | 13 | 9 | 2 | 2 | 5 | 8 | 11 | +1 | 22 |
| 8 | DC United | 16 | 5 | 0 | 2 | 12 | 4 | 1 | 3 | 5 | 9 | 14 | +3 | 21 |
| 9 | NY Red Bulls | 15 | 4 | 1 | 2 | 12 | 7 | 1 | 2 | 5 | 8 | 13 | 0 | 18 |
| 10 | Atlanta U | 16 | 2 | 3 | 2 | 8 | 7 | 0 | 5 | 4 | 8 | 14 | -5 | 14 |
| 11 | Toronto FC | 16 | 1 | 4 | 2 | 9 | 10 | 2 | 1 | 6 | 12 | 23 | -12 | 14 |
| 12 | Cincinnati | 15 | 0 | 3 | 3 | 5 | 9 | 3 | 2 | 4 | 12 | 20 | -12 | 14 |
| 13 | Chicago | 16 | 3 | 3 | 4 | 15 | 14 | 0 | 1 | 5 | 3 | 14 | -10 | 13 |
| 14 | Inter Miami CF | 14 | 1 | 2 | 5 | 7 | 18 | 2 | 1 | 3 | 5 | 6 | -12 | 12 |
| 15 | Seattle | 17 | 5 | 3 | 2 | 17 | 8 | 4 | 2 | 1 | 8 | 5 | +12 | 32 |
| 16 | Kansas City | 16 | 5 | 3 | 1 | 17 | 10 | 4 | 0 | 3 | 12 | 9 | +10 | 30 |
| 17 | LA Galaxy | 16 | 6 | 0 | 2 | 16 | 9 | 3 | 1 | 4 | 11 | 18 | 0 | 28 |
| 18 | Colorado | 15 | 5 | 2 | 1 | 16 | 8 | 3 | 1 | 3 | 6 | 8 | +6 | 27 |
| 19 | Los Angeles FC | 16 | 4 | 4 | 1 | 15 | 10 | 2 | 1 | 4 | 7 | 9 | +3 | 23 |
| 20 | Minnesota U | 16 | 5 | 1 | 2 | 10 | 6 | 1 | 4 | 3 | 9 | 15 | -2 | 23 |
| 21 | Real Salt Lake | 15 | 3 | 4 | 2 | 14 | 9 | 2 | 2 | 2 | 10 | 7 | +8 | 21 |
| 22 | Portland Timb. | 15 | 5 | 0 | 2 | 11 | 6 | 1 | 1 | 6 | 8 | 20 | -7 | 19 |
| 23 | Houston | 16 | 3 | 4 | 0 | 9 | 6 | 0 | 5 | 4 | 8 | 14 | -3 | 18 |
| 24 | Dallas | 16 | 3 | 5 | 0 | 16 | 8 | 1 | 0 | 7 | 4 | 16 | -4 | 17 |
| 25 | San Jose | 16 | 2 | 1 | 4 | 10 | 12 | 2 | 4 | 3 | 8 | 13 | -7 | 17 |
| 26 | Vancouver W | 16 | 3 | 2 | 3 | 8 | 10 | 0 | 4 | 4 | 10 | 17 | -9 | 15 |
| 27 | Austin FC | 15 | 1 | 2 | 3 | 4 | 5 | 2 | 2 | 5 | 6 | 11 | -6 | 13 |
